Ipamorelin

$80.00

Ipamorelin is a synthetic pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH₂) designed as a highly selective growth hormone secretagogue, incorporating non-natural amino acids such as Aib (aminoisobutyric acid) and D-2-Nal for superior receptor specificity, metabolic stability, and minimal off-target hormonal effects.

 

  • Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH₂ (5 amino acids)
  • Key Features: Non-natural residues (Aib, D-2-Nal) for high selectivity and stability
  • Research Focus Areas: Selective GH release profiles, minimal impact on prolactin/ACTH/cortisol, bone density and repair models, appetite and metabolic contrasts
  • Common Models: In vitro pituitary assays, rodent endocrine profiling, post-operative ileus paradigms, bone regeneration studies
  • Mechanistic Interests: GHSR-1a activation with high GH exclusivity, calcium mobilization, negligible effects on stress hormones

It is used in research to explore ghrelin receptor (GHSR-1a) engagement, intracellular calcium signaling, targeted growth hormone stimulation, and downstream endocrine pathways in pituitary and metabolic model systems, often contrasted with less selective GHS compounds for studies on specificity and long-term axis modulation.

All products currently listed on this site are for research purposes only.

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Ipamorelin