Humanin
Overview
Research-use mitochondria-derived peptide supplied for studies of cellular stress-response, metabolic signaling, and survival pathway models.
- Concentration
- 10 mg
- Stock
- In stock
Product details
Humanin is a mitochondria-derived peptide used in research models of cellular stress response, metabolic signaling, and survival pathways. Pattern lists this material for controlled laboratory research.
Research Targets: Mitochondrial signaling, FPRL1-associated pathways, CNTFR complex models, insulin-signaling pathway markers.
Key Feature: Mitochondria-derived peptide used for cytoprotection-model research.
Research Focus Areas: Cellular stress-response models, metabolic signaling, neuroprotection pathway studies, mitochondrial communication research.
Common Models: Neuronal culture assays, metabolic disorder models, mitochondrial stress experiments.
Mechanistic Interests: Anti-apoptotic signaling markers, mitochondrial-nuclear communication, oxidative-stress response, insulin-sensitivity pathway markers.
Use Boundary: Research use only; not for human or veterinary use; no diagnostic, therapeutic, or consumption use is implied.
Research context
Peptide guide
Open full guide- Guide profile
- Mitochondrial-Derived Peptide
- Composition
- Small mitochondrial-derived peptide (MDP) consisting of 24 amino acids (sequence: MAPRGFSCLLLLTSEIDLPVKRRA), encoded within the 16S ribosomal RNA gene (MT-RNR2) of the mitochondrial genome
- Discovery
- Discovered in 2001 by multiple independent research groups, most notably the Nishimoto lab, during a functional screening of cDNA from the relatively spared occipital lobe of an Alzheimer's disease patient's brain
- Research scope
- Preclinical studies (in vitro cell cultures, rodent models, and other animals) dominate the evidence base, demonstrating Humanin's cytoprotective roles
- Regulatory status
- No large-scale clinical approvals; human efficacy data are scarce
Safety context
- Limited data; caution in metabolic disorders or with glucose-altering agents
- No FDA approval or extensive human clinical validation for therapeutic use
Research-use notice: Humanin is best framed as a mitochondrial-derived peptide research topic rather than an established therapy. Preclinical and observational evidence covers neurodegeneration, cardiovascular biology, metabolism, and aging pathways, but it lacks FDA approval and extensive interventional human validation. Clinical decisions require qualified medical oversight.
Full guide includes 10 reference entries.
One kit adds 10 vials to WooCommerce checkout.