MOTS-C
Overview
Research-use mitochondrial-derived peptide supplied for studies of metabolic stress signaling, AMPK pathway biology, and energy-homeostasis models.
- Concentration
- 10 mg
- Stock
- In stock
Product details
MOTS-c is a mitochondrial-derived peptide encoded within the mitochondrial 12S rRNA region and used in metabolic stress-signaling research models. Pattern lists this material for controlled laboratory research.
Research Targets: AMPK-associated signaling, folate-purine metabolism, mitochondrial stress response, nuclear gene-expression models.
Key Feature: Mitochondrial-derived peptide format for metabolic signaling research.
Research Focus Areas: Metabolic homeostasis, energy-sensing pathways, muscle cell metabolism, aging-associated pathway models.
Common Models: Muscle cell assays, diet-induced metabolic models, mitochondrial stress experiments.
Mechanistic Interests: AMPK pathway activation markers, mitochondrial-nuclear communication, folate-purine pathway interactions, stress-responsive gene regulation.
Use Boundary: Research use only; not for human or veterinary use; no diagnostic, therapeutic, or consumption use is implied.
Product documentation
Certificate of Analysis
MOTS-c
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Research context
Peptide guide
Open full guide- Guide profile
- Mitochondrial Open Reading Frame of the 12S rRNA-c
- Composition
- 16-amino-acid cyclic peptide encoded directly within the mitochondrial genome (mitochondrial 12S rRNA region)
- Discovery
- Identified in the early 2010s by researchers exploring mitochondrial-encoded peptides and their extramitochondrial roles in systemic metabolism
- Research scope
- Foundation of knowledge comes from animal models (mice, cell cultures), showing improvements in insulin sensitivity, protection against diet-induced obesity, enhanced fatty acid oxidation, increased AMPK activation, and better mitochondrial efficiency
- Regulatory status
- Not approved by regulatory agencies for therapeutic use; wellness and performance claims exceed the available human evidence
Safety context
- Not approved for human use
- Limited long-term safety data
- Not intended to diagnose, treat, or cure any disease
Research-use notice: MOTS-c is an investigational mitochondrial-derived peptide with mostly preclinical support for metabolic-stress and energy-balance biology. It lacks approval from major regulatory bodies for human use, and long-term human safety data remain limited. Potential risks, including unknown long-term effects on mitochondrial signaling, remain understudied, so clinical decisions require qualified medical oversight.
Full guide includes 10 reference entries.
One kit adds 10 vials to WooCommerce checkout.