Product profile
PT-141
Overview
A melanocortin receptor-targeting cyclic peptide researched for its role in central arousal pathway signaling, hypothalamic neuromodulation, and autonomic nervous system activation.
- Concentration
- 10 mg
- Stock
- In stock
Product details
PT-141 (Bremelanotide) is a synthetic cyclic heptapeptide analogue of alpha-melanocyte-stimulating hormone (α-MSH), investigated for its activity at central melanocortin receptors. Unlike peripherally acting compounds, it engages CNS-mediated pathways, making it a research tool for studying hypothalamic neuromodulation, autonomic signaling, and centrally regulated physiological responses.
- Receptor Targets: Melanocortin receptors MC3R and MC4R (CNS-expressed), hypothalamic neuropeptide signaling networks
- Key Feature: CNS-active melanocortin agonist with hypothalamic neuromodulatory activity
- Research Focus Areas: Central arousal pathway regulation, hypothalamic signaling, autonomic nervous system modulation, melanocortin system biology
- Common Models: Hypothalamic receptor binding studies, CNS neuromodulation models, autonomic response paradigms, melanocortin pathway studies
- Mechanistic Interests: MC3R/MC4R agonism, dopaminergic and oxytocinergic pathway crosstalk, cAMP-mediated intracellular signaling, hypothalamic-autonomic axis activation
It is used in research to explore melanocortin receptor biology, central neuromodulatory signaling, and hypothalamic regulation of autonomic physiological pathways.
All products currently listed on this site are for research purposes only.
